Genomic Location: chr_5:5310267...5364637
NR annotation: XP_020913554.1, rho guanine nucleotide exchange factor 12 isoform X9 [Exaiptasia diaphana]
| CDS | |
| alvinactis_v1_g10318 | |
| Transcript |
| alvinactis_v1_g10318 |
| Protein |
| alvinactis_v1_g10318 |
| Uniprot term | Description |
|---|---|
| Q9NZN5 | Rho guanine nucleotide exchange factor 12 OS=Homo sapiens OX=9606 GN=ARHGEF12 PE=1 SV=1 |
| Q8R4H2 | Rho guanine nucleotide exchange factor 12 OS=Mus musculus OX=10090 GN=Arhgef12 PE=1 SV=2 |
| O15085 | Rho guanine nucleotide exchange factor 11 OS=Homo sapiens OX=9606 GN=ARHGEF11 PE=1 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00130 | C1_1 | Phorbol esters/diacylglycerol binding domain (C1 domain) | Domain | Interproscan |
| PF17838 | PH_16 | PH domain | Domain | Interproscan |
| PF09128 | RGS-like | Regulator of G protein signalling-like domain | Domain | Interproscan |
| PF00621 | RhoGEF | RhoGEF domain | Domain | Interproscan |
| PF00595 | PDZ | PDZ domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR000219 | Domain | Dbl homology (DH) domain | Interproscan |
| IPR036034 | Homologous_superfamily | PDZ superfamily | Interproscan |
| IPR002219 | Domain | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | Interproscan |
| IPR035899 | Homologous_superfamily | Dbl homology (DH) domain superfamily | Interproscan |
| IPR041020 | Domain | ARHGEF1-like, PH domain | Interproscan |
| IPR015212 | Domain | Regulator of G protein signalling-like domain | Interproscan |
| IPR036305 | Homologous_superfamily | RGS domain superfamily | Interproscan |
| IPR011993 | Homologous_superfamily | PH-like domain superfamily | Interproscan |
| IPR046349 | Homologous_superfamily | C1-like domain superfamily | Interproscan |
| IPR016137 | Domain | RGS domain | Interproscan |
| IPR001478 | Domain | PDZ domain | Interproscan |
| IPR001849 | Domain | Pleckstrin homology domain | Interproscan |
| IPR044926 | Homologous_superfamily | RGS, subdomain 2 | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR45872 | RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 2, ISOFORM D | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0005085 | Molecular Function | guanyl-nucleotide exchange factor activity | Interproscan |
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0005737 | Cellular Component | cytoplasm | Interproscan |
| GO:0001664 | Molecular Function | G protein-coupled receptor binding | Interproscan |
| GO:0007186 | Biological Process | G protein-coupled receptor signaling pathway | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K07532 | ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12 | - | Membrane trafficking | ko04131 | deepkoala |