Genomic Location: chr_2:4237927...4239372
NR annotation: XP_020905893.1, methyl-CpG-binding domain protein 3 [Exaiptasia diaphana]
| CDS | |||||
| alvinactis_v1_g3063 | |||||
| Transcript |
| alvinactis_v1_g3063 |
| Protein |
| alvinactis_v1_g3063 |
| Uniprot term | Description |
|---|---|
| Q9Z2E1 | Methyl-CpG-binding domain protein 2 OS=Mus musculus OX=10090 GN=Mbd2 PE=1 SV=2 |
| Q9UBB5 | Methyl-CpG-binding domain protein 2 OS=Homo sapiens OX=9606 GN=MBD2 PE=1 SV=1 |
| Q9Z2D8 | Methyl-CpG-binding domain protein 3 OS=Mus musculus OX=10090 GN=Mbd3 PE=1 SV=1 |
| Gene family | Subfamily |
|---|---|
| Transcription Factors Family | MBD |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF14048 | MBD_C | C-terminal domain of methyl-CpG binding protein 2 and 3 | Family | Interproscan |
| PF01429 | MBD | Methyl-CpG binding domain | Domain | Interproscan |
| PF16564 | MBDa | p55-binding region of Methyl-CpG-binding domain proteins MBD | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR025884 | Domain | Methyl-CpG binding protein 2/3, C-terminal domain | Interproscan |
| IPR001739 | Domain | Methyl-CpG DNA binding | Interproscan |
| IPR016177 | Homologous_superfamily | DNA-binding domain superfamily | Interproscan |
| IPR032343 | Domain | Methyl-CpG-binding domain protein 2/3, p55-binding region | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR12396 | METHYL-CPG BINDING PROTEIN, MBD | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0000122 | Biological Process | negative regulation of transcription by RNA polymerase II | Interproscan |
| GO:0005634 | Cellular Component | nucleus | Interproscan |
| GO:0006346 | Biological Process | DNA methylation-dependent constitutive heterochromatin formation | Interproscan |
| GO:0008327 | Molecular Function | methyl-CpG binding | Interproscan |
| GO:0003677 | Molecular Function | DNA binding | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K11590 | MBD2; methyl-CpG-binding domain protein 2 | - | Chromosome and associated proteins | ko03036 | deepkoala |