Genomic Location: chr11:13004813...13033464
NR annotation: XP_028514626.1, histone-lysine N-methyltransferase SETDB1 [Exaiptasia diaphana]
| CDS | |||||
| gene08653.t1 | |||||
| Transcript |
| gene08653.t1 |
| Protein |
| gene08653.t1 |
| Uniprot term | Description |
|---|---|
| Q32KD2 | Histone-lysine N-methyltransferase eggless OS=Drosophila melanogaster OX=7227 GN=egg PE=1 SV=1 |
| Q28Z18 | Histone-lysine N-methyltransferase eggless OS=Drosophila pseudoobscura pseudoobscura OX=46245 GN=egg PE=3 SV=2 |
| O88974 | Histone-lysine N-methyltransferase SETDB1 OS=Mus musculus OX=10090 GN=Setdb1 PE=1 SV=1 |
| Gene family | Subfamily |
|---|---|
| Transcription Factors Family | MBD |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF18359 | Tudor_5 | Histone methyltransferase Tudor domain 1 | Domain | Interproscan |
| PF01429 | MBD | Methyl-CpG binding domain | Domain | Interproscan |
| PF00856 | SET | SET domain | Family | Interproscan |
| PF18358 | Tudor_4 | Histone methyltransferase Tudor domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR041291 | Domain | Histone methyltransferase, Tudor domain 1 | Interproscan |
| IPR046341 | Homologous_superfamily | SET domain superfamily | Interproscan |
| IPR001739 | Domain | Methyl-CpG DNA binding | Interproscan |
| IPR003616 | Domain | Post-SET domain | Interproscan |
| IPR007728 | Domain | Pre-SET domain | Interproscan |
| IPR001214 | Domain | SET domain | Interproscan |
| IPR041292 | Domain | Histone methyltransferase, Tudor domain 2 | Interproscan |
| IPR051516 | Family | Histone-lysine N-methyltransferase SETDB | Interproscan |
| IPR016177 | Homologous_superfamily | DNA-binding domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR46024 | HISTONE-LYSINE N-METHYLTRANSFERASE EGGLESS | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0003677 | Molecular Function | DNA binding | Interproscan |
| GO:0005634 | Cellular Component | nucleus | Interproscan |
| GO:0008270 | Molecular Function | zinc ion binding | Interproscan |
| GO:0042054 | Molecular Function | histone methyltransferase activity | Interproscan |
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0010629 | Biological Process | negative regulation of gene expression | Interproscan |
| GO:0046974 | Molecular Function | histone H3K9 methyltransferase activity | Interproscan |
| GO:0051567 | Biological Process | obsolete histone H3-K9 methylation | Interproscan |
| GO:0070828 | Biological Process | heterochromatin organization | Interproscan |
| GO:0090309 | Biological Process | obsolete positive regulation of DNA methylation-dependent heterochromatin formation | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K11421 | SETDB1; [histone H3]-N6,N6-dimethyl-lysine9 N-methyltransferase | EC:2.1.1.366 | Chromosome and associated proteins | ko03036 | deepkoala |