Genomic Location: chr4:12536112...12550555
NR annotation: XP_020906776.1, guanine nucleotide exchange factor VAV2 isoform X2 [Exaiptasia diaphana]
| CDS | ||||
| gene14340.t2 | ||||
| Transcript |
| gene14340.t2 |
| Protein |
| gene14340.t2 |
| Uniprot term | Description |
|---|---|
| Q45FX5 | Protein vav-1 OS=Caenorhabditis elegans OX=6239 GN=vav-1 PE=1 SV=1 |
| P27870 | Proto-oncogene vav OS=Mus musculus OX=10090 GN=Vav1 PE=1 SV=1 |
| P52735 | Guanine nucleotide exchange factor VAV2 OS=Homo sapiens OX=9606 GN=VAV2 PE=1 SV=2 |
| Gene family | Subfamily |
|---|---|
| Ubiquitin Family | UBD|Other|SH3 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00130 | C1_1 | Phorbol esters/diacylglycerol binding domain (C1 domain) | Domain | Interproscan |
| PF00018 | SH3_1 | SH3 domain | Domain | Interproscan |
| PF00017 | SH2 | SH2 domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR000980 | Domain | SH2 domain | Interproscan |
| IPR002219 | Domain | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | Interproscan |
| IPR001452 | Domain | SH3 domain | Interproscan |
| IPR036860 | Homologous_superfamily | SH2 domain superfamily | Interproscan |
| IPR036028 | Homologous_superfamily | SH3-like domain superfamily | Interproscan |
| IPR046349 | Homologous_superfamily | C1-like domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR45818 | PROTEIN VAV | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0005085 | Molecular Function | guanyl-nucleotide exchange factor activity | Interproscan |
| GO:0005737 | Cellular Component | cytoplasm | Interproscan |
| GO:0016477 | Biological Process | cell migration | Interproscan |
| GO:0043087 | Biological Process | regulation of GTPase activity | Interproscan |